MedKoo Cat#: 561392 | Name: Sul-121 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sul-121 is a novel compound with anti-oxidative capacity. Sul-121 HCl inhibits airway inflammation and hyperresponsiveness (AHR) in experimental chronic obstructive pulmonary disease (COPD) models, prospectively through inhibition of oxidative stress.

Chemical Structure

Sul-121 HCl
Sul-121 HCl
CAS#1541170-25-5

Theoretical Analysis

MedKoo Cat#: 561392

Name: Sul-121 HCl

CAS#: 1541170-25-5

Chemical Formula: C18H27ClN2O3

Exact Mass:

Molecular Weight: 354.88

Elemental Analysis: C, 60.92; H, 7.67; Cl, 9.99; N, 7.89; O, 13.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Sul-121 HCl; Sul121 HCl; Sul 121 HCl; Sul-121 Hydrochloride;
IUPAC/Chemical Name
6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl (piperazin-1-yl)methanone Hydrochloride
InChi Key
PLQHNEVLWPLIKP-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H26N2O3.ClH/c1-11-12(2)16-14(13(3)15(11)21)5-6-18(4,23-16)17(22)20-9-7-19-8-10-20;/h19,21H,5-10H2,1-4H3;1H
SMILES Code
O=C(C1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C)N3CCNCC3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 354.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Han B, Poppinga WJ, Zuo H, Zuidhof AB, Bos IS, Smit M, Vogelaar P, Krenning G, Henning RH, Maarsingh H, Halayko AJ, van Vliet B, Stienstra S, Graaf AC, Meurs H, Schmidt M. The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. Sci Rep. 2016 May 27;6:26928. doi: 10.1038/srep26928. PubMed PMID: 27229886; PubMed Central PMCID: PMC4882609.