MedKoo Cat#: 561382 | Name: iCRT5
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

iCRT5 is a cell-permeable β-catenin-responsive transcription (CRT) inhibitor. iCRT5 disrupts the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin.

Chemical Structure

iCRT5
iCRT5
CAS#18623-44-4

Theoretical Analysis

MedKoo Cat#: 561382

Name: iCRT5

CAS#: 18623-44-4

Chemical Formula: C16H17NO5S2

Exact Mass: 367.0548

Molecular Weight: 367.43

Elemental Analysis: C, 52.30; H, 4.66; N, 3.81; O, 21.77; S, 17.45

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
iCRT5; iCRT-5; iCRT 5; CRT Inhibitor iCRT5
IUPAC/Chemical Name
(Z)-4-(5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
InChi Key
IJWKSBPTJQMUHJ-LCYFTJDESA-N
InChi Code
InChI=1S/C16H17NO5S2/c1-21-11-6-5-10(8-12(11)22-2)9-13-15(20)17(16(23)24-13)7-3-4-14(18)19/h5-6,8-9H,3-4,7H2,1-2H3,(H,18,19)/b13-9-
SMILES Code
O=C(O)CCCN(C/1=O)C(SC1=C/C2=CC=C(OC)C(OC)=C2)=S
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 367.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL