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MedKoo Cat#: 571238 | Name: Propyliodone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Propyliodone is a radiopaque medium usually in oil that is used in bronchography. It is a diagnostic aid. It may induce hyperthyroidism.

Chemical Structure

Propyliodone
Propyliodone
CAS#587-61-1

Theoretical Analysis

MedKoo Cat#: 571238

Name: Propyliodone

CAS#: 587-61-1

Chemical Formula: C10H11I2NO3

Exact Mass: 446.8828

Molecular Weight: 447.01

Elemental Analysis: C, 26.87; H, 2.48; I, 56.78; N, 3.13; O, 10.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Propyliodone; NSC 97103; NSC-97103; NSC97103
IUPAC/Chemical Name
1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, propyl ester
InChi Key
ROSXARVHJNYYDO-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H11I2NO3/c1-2-3-16-9(14)6-13-4-7(11)10(15)8(12)5-13/h4-5H,2-3,6H2,1H3
SMILES Code
O=C(OCCC)CN(C=C1I)C=C(I)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 447.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Benker G, Vosskühler A, Hoff HG, Windeck R, Reinwein D, Klein E. Thyroid function after bronchography with propyliodone. Horm Res. 1983;17(3):121-7. PubMed PMID: 6406336. 2: Ossowska K, Trzebińska-Korniszewska A. [Complications following bronchography performed with propyliodone]. Pneumonol Pol. 1976 May;44(5):481-4. Polish. PubMed PMID: 1272895. 3: HSING CT, HAN FC. Clinical observation of bronchography with propyliodone (Dionosil). Dis Chest. 1963 Feb;43:186-92. PubMed PMID: 13955293. 4: Braunstein E. Inadvertent intrasplenic injection of oily propyliodone. AJR Am J Roentgenol. 1977 Jul;129(1):152-3. PubMed PMID: 409129. 5: GOMBERT HJ, HOFFMANN R. [Propyliodone (Cilag), an isotonic aqueous contrast medium suspension for bronchography]. Fortschr Geb Rontgenstr. 1955 Oct;83(4):559-62. German. PubMed PMID: 13285599. 6: ERBSLOEH J. [The double contrast method in hysterography with the aid of propyliodone]. Fortschr Geb Rontgenstr Nuklearmed. 1959 Aug;91:249-52. German. PubMed PMID: 13849727. 7: PFEIFER W, SEIDEL K. [Experiences with propyliodone bronchography]. Med Klin. 1958 Feb 21;53(8):293-5. English, German. PubMed PMID: 13540854. 8: Chawla BS. Thixotropy and rheopexy of propyliodone suspensions in arachis oil: effect of median particle size. J Pharm Pharmacol. 1968 Dec;20:Suppl:168S+. PubMed PMID: 4388152. 9: SVOBODA M. [Bronchography with propyliodone]. Cesk Rentgenol. 1956 Mar;10(1):37-9. Czech. PubMed PMID: 13316935. 10: Bryc S, Zlomaniec J. [Use of propyliodone in the diagnosis of esophageal trauma]. Pol Przegl Chir. 1976;48(5):637-40. Polish. PubMed PMID: 1272995. 11: MALASPINA A, MERLO G, SAVINO G. [A new aqueous contrast medium for bronchography: propyliodone-barium]. Minerva Med. 1959 Dec 1;50:3905-13. Italian. PubMed PMID: 14420234. 12: DI GUGLIELMO L, CATTANEO L, COUCOURDE F. [New contrast medium for bronchography: propyliodone]. Minerva Med. 1958 Sep 8;49(72):3418-23. Italian. PubMed PMID: 13600150. 13: WILLSON JK, PERILLA FR, HANCHETT RB. Bronchography with dionosil (propyliodone); a new absorbable bronchographic medium. Am J Roentgenol Radium Ther Nucl Med. 1956 Apr;75(4):720-7. PubMed PMID: 13302535. 14: TOMICH EG, BASIL B, DAVIS B. The properties of n-propyl 3:5-di-iodo-4-pyridone-N-acetate (propyliodone). Br J Pharmacol Chemother. 1953 Jun;8(2):166-70. PubMed PMID: 13066716; PubMed Central PMCID: PMC1509345. 15: VARLAMOVA LS, POZHARSKAIA AM. [OIL SUSPENSIONS OF PROPYLIODONE]. Med Prom SSSR. 1963 Oct;17:37-8. Russian. PubMed PMID: 14122734. 16: Zhang ZM. [Experience of selective bronchography using propyliodone]. Zhonghua Fang She Xue Za Zhi. 1988 Aug;22(4):212-5. Chinese. PubMed PMID: 3208581. 17: GRABIGER R. [On retention of contrast medium after bronchography with propyliodone Cilag]. Fortschr Geb Rontgenstr Nuklearmed. 1960 Dec;93:801-3. German. PubMed PMID: 13707617. 18: PISANI G, MALASPINA A, MERLO G. [Experimentation on barium sulfate and iodated ester in aqueous suspensions (propyliodone-barium) in bronchography]. Ann Otolaryngol. 1960 Mar;77:141-6. French. PubMed PMID: 14433245. 19: Thompson IM, Whittlesey GC, Slovis TL, Chang CH, Cullen ML, Philippart AI, Stockmann PS, Adkins ES, Klein MD. Evaluation of contrast media for bronchography. Pediatr Radiol. 1997 Jul;27(7):598-605. PubMed PMID: 9211957. 20: SCHNEIDRZIK WE, SCHULTE W. [Infraglottic bronchography with propyliodone as a routine examination; a simple and conservative method]. Munch Med Wochenschr. 1956 Feb 24;98(8):274-8. German. PubMed PMID: 13309307.