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MedKoo Cat#: 561345 | Name: NPD7155

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NPD7155 is a competitive MTH1 inhibitor.

Chemical Structure

NPD7155
NPD7155
CAS#924764-38-5

Theoretical Analysis

MedKoo Cat#: 561345

Name: NPD7155

CAS#: 924764-38-5

Chemical Formula: C15H21N5

Exact Mass: 271.1797

Molecular Weight: 271.37

Elemental Analysis: C, 66.39; H, 7.80; N, 25.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NPD7155; NPD-7155; NPD 7155;
IUPAC/Chemical Name
1,3,3-Trimethyl-6-(9H-purin-6-yl)-6-azabicyclo[3.2.1]octane
InChi Key
JWPIQIKLBJGZHZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H21N5/c1-14(2)4-10-5-15(3,6-14)7-20(10)13-11-12(17-8-16-11)18-9-19-13/h8-10H,4-7H2,1-3H3,(H,16,17,18,19)
SMILES Code
CC1(C)CC(C2)(C)CN(C3=C4N=CNC4=NC=N3)C2C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 271.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanaka M, Honda K, Osada H. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival. Sci Rep. 2016 May 23;6:26521. doi: 10.1038/srep26521. PubMed PMID: 27210421; PubMed Central PMCID: PMC4876372.