FMK-9a is a covalent ATG4B (Autophagin-1) inhibitor. ATG4B or autophagin-1 is a cysteine protease that cleaves ATG8 family proteins. ATG4B plays essential roles in the autophagosome formation and the autophagy pathway.
MedKoo Cat#: 561337
Name: FMK-9a
CAS#: 1955550-51-2
Chemical Formula: C23H21FN2O3
Exact Mass: 392.1536
Molecular Weight: 392.43
Elemental Analysis: C, 70.40; H, 5.39; F, 4.84; N, 7.14; O, 12.23
The following data is based on the product molecular weight 392.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
