Synonym
15-Hexadecynoic acid; 15 Hexadecynoic acid; 15Hexadecynoic acid; Alkynyl Palmitic Acid
IUPAC/Chemical Name
Hexadec-15-ynoic acid
InChi Key
PUZGUNYANHPRKM-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h1H,3-15H2,(H,17,18)
SMILES Code
C#CCCCCCCCCCCCCCC(O)=O
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
252.40
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Ebersole B, Petko J, Levenson R. Bioorthogonal click chemistry to assay mu-opioid receptor palmitoylation using 15-hexadecynoic acid and immunoprecipitation. Anal Biochem. 2014 Apr 15;451:25-7. doi: 10.1016/j.ab.2014.01.008. Epub 2014 Jan 23. PubMed PMID: 24463015; PubMed Central PMCID: PMC3969759.
3: Aitken AE, Roman LJ, Loughran PA, de la Garza M, Masters BS. Expressed CYP4A4 metabolism of prostaglandin E(1) and arachidonic acid. Arch Biochem Biophys. 2001 Sep 15;393(2):329-38. PubMed PMID: 11556821.
4: Shak S, Reich NO, Goldstein IM, Ortiz de Montellano PR. Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids. J Biol Chem. 1985 Oct 25;260(24):13023-8. PubMed PMID: 2997155.
