Synonym
Delprostenate; A 2774; A2774; A-2774
IUPAC/Chemical Name
2,5-Heptadienoic acid, 7-(2-(4-(3-chlorophenoxy)-3-hydroxy-1-butenyl)-3,5- dihydroxycyclopentyl)-, methyl ester, (1R-(1-alpha(2E,5Z),2-beta(1E,3R*),3-alpha,5-alpha))-
InChi Key
FNAMRDZHKYQEBA-CIVCTDFYSA-N
InChi Code
InChI=1S/C23H29ClO6/c1-29-23(28)10-5-3-2-4-9-19-20(22(27)14-21(19)26)12-11-17(25)15-30-18-8-6-7-16(24)13-18/h2,4-8,10-13,17,19-22,25-27H,3,9,14-15H2,1H3/b4-2-,10-5+,12-11+/t17?,19-,20-,21+,22-/m1/s1
SMILES Code
O=C(OC)/C=C/C/C=C\C[C@@H]1[C@@H](/C=C/C(O)COC2=CC=CC(Cl)=C2)[C@H](O)C[C@@H]1O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
436.93
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: Tsutsui T, Kawakami E, Orima H, Yamauchi M, Okubo T, Stabenfeldt GH. Effects of prostaglandin F2 alpha-analogue administration on luteal function, implantation of embryos and maintenance of pregnancy in bitches. Nihon Juigaku Zasshi. 1989 Jun;51(3):496-504. PubMed PMID: 2761141.
8: Vilariño M, Cuadro F, Dos Santos-Neto PC, García-Pintos C, Menchaca A. Time of ovulation and pregnancy outcomes obtained with the prostaglandin-based protocol Synchrovine for FTAI in sheep. Theriogenology. 2017 Mar 1;90:163-168. doi: 10.1016/j.theriogenology.2016.12.003. Epub 2016 Dec 3. PubMed PMID: 28166963.
