Leucettamol A is a A leukotriene B4 receptor antagonist isolated from the marine sponge Leucetta microraphis.It has a structure of a chiral long-chain "two-headed" sphingolipid (dimeric sphingolipid). It inhibits the formation of a complex composed of the ubiquitin E2 enzyme Ubc13 and Uev1A. The post-translational modification of proteins with ubiquitin (Ub) controls a number of fundamental processes within the cell, including protein degradation by the Ub−proteasome system (UPS). These inhibitors may be leads for anti-cancer agents and anti-rheumatoid arthritis agents.
MedKoo Cat#: 571061
Name: Leucettamol A
CAS#: 151124-32-2
Chemical Formula: C30H52N2O2
Exact Mass: 472.4029
Molecular Weight: 472.76
Elemental Analysis: C, 76.22; H, 11.09; N, 5.93; O, 6.77
The following data is based on the product molecular weight 472.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
