CeMMEC13 is a selective inhibitor of TAF1. CeMMEC13 acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
MedKoo Cat#: 561259
Name: CeMMEC13
CAS#: 1790895-25-8
Chemical Formula: C19H16N2O4
Exact Mass: 336.1110
Molecular Weight: 336.35
Elemental Analysis: C, 67.85; H, 4.80; N, 8.33; O, 19.03
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.0 | 59.50 |
The following data is based on the product molecular weight 336.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
