MedKoo Cat#: 561247 | Name: IDD388
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IDD388 is an aldose reductase (AR) inhibitor.

Chemical Structure

IDD388
IDD388
CAS#314297-26-2

Theoretical Analysis

MedKoo Cat#: 561247

Name: IDD388

CAS#: 314297-26-2

Chemical Formula: C16H12BrClFNO4

Exact Mass: 414.9622

Molecular Weight: 416.63

Elemental Analysis: C, 46.13; H, 2.90; Br, 19.18; Cl, 8.51; F, 4.56; N, 3.36; O, 15.36

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,350.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 7,650.00 2 Weeks
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Related CAS #
No Data
Synonym
IDD388; IDD 388; IDD-388
IUPAC/Chemical Name
2-(2-((4-bromo-2-fluorobenzyl)carbamoyl)-5-chlorophenoxy)acetic acid
InChi Key
ZLIGBZRXAQNUFO-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H12BrClFNO4/c17-10-2-1-9(13(19)5-10)7-20-16(23)12-4-3-11(18)6-14(12)24-8-15(21)22/h1-6H,7-8H2,(H,20,23)(H,21,22)
SMILES Code
O=C(O)COC1=CC(Cl)=CC=C1C(NCC2=CC=C(Br)C=C2F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cousido-Siah A, Ruiz FX, Fanfrlík J, Giménez-Dejoz J, Mitschler A, Kamlar M, Veselý J, Ajani H, Parés X, Farrés J, Hobza P, Podjarny AD. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705. Epub 2016 Aug 5. PubMed PMID: 27359042. 2: Steuber H, Heine A, Podjarny A, Klebe G. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J Mol Biol. 2008 Jun 20;379(5):991-1016. doi: 10.1016/j.jmb.2008.03.063. Epub 2008 Apr 8. PubMed PMID: 18495158.