MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 571024 | Name: Flucycloxuron
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flucycloxuron is a chitin synthesis inhibitor used as a pesticide. In insect models, the inhibitor has been shown to affect several reproductive events such as the duration of preovipostion and oviposition period, the fecundity, the viability of eggs and the duration of embryonic development, respectively.

Chemical Structure

Flucycloxuron
Flucycloxuron
CAS#113036-88-7

Theoretical Analysis

MedKoo Cat#: 571024

Name: Flucycloxuron

CAS#: 113036-88-7

Chemical Formula: C25H20ClF2N3O3

Exact Mass: 483.1161

Molecular Weight: 483.90

Elemental Analysis: C, 62.05; H, 4.17; Cl, 7.33; F, 7.85; N, 8.68; O, 9.92

Price and Availability

Size Price Availability Quantity
25mg USD 650.00 Back order
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Flucycloxuron; Andalin
IUPAC/Chemical Name
Benzamide, N-(((4-(((((4-chlorophenyl)cyclopropylmethylene)amino)oxy)methyl)phenyl)amino)carbonyl)-2,6-difluoro-
InChi Key
PCKNFPQPGUWFHO-SXBRIOAWSA-N
InChi Code
InChI=1S/C25H20ClF2N3O3/c26-18-10-8-17(9-11-18)23(16-6-7-16)31-34-14-15-4-12-19(13-5-15)29-25(33)30-24(32)22-20(27)2-1-3-21(22)28/h1-5,8-13,16H,6-7,14H2,(H2,29,30,32,33)/b31-23-
SMILES Code
O=C(NC(NC1=CC=C(CO/N=C(C2=CC=C(Cl)C=C2)/C3CC3)C=C1)=O)C4=C(F)C=CC=C4F
Appearance
Solid powder
Purity
>90% (mixture of (E) and (Z) isomers)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 483.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rouabhi R, Berrebbah H, Djebar MR. Evaluation of toxicity of two pesticides: flucycloxuron and diflubenzuron on a cellular model, Paramecium sp. Commun Agric Appl Biol Sci. 2006;71(2 Pt A):83-90. PubMed PMID: 17390777. 2: Sun R, Wang Z, Li Y, Xiong L, Liu Y, Wang Q. Design, synthesis, and insecticidal evaluation of new benzoylureas containing amide and sulfonate groups based on the sulfonylurea receptor protein binding site for diflubenzuron and glibenclamide. J Agric Food Chem. 2013 Jan 23;61(3):517-22. doi: 10.1021/jf304468b. Epub 2013 Jan 10. PubMed PMID: 23305601. 3: Hami M, Taibi F, Soltani-Mazouni N. Effects of flucycloxuron, a chitin synthesis inhibitor, on reproductive events and thickness of chorion in mealworms. Commun Agric Appl Biol Sci. 2004;69(3):249-55. PubMed PMID: 15759421. 4: Sun R, Li Y, Xiong L, Liu Y, Wang Q. Design, synthesis, and insecticidal evaluation of new benzoylureas containing isoxazoline and isoxazole group. J Agric Food Chem. 2011 May 11;59(9):4851-9. doi: 10.1021/jf200395g. Epub 2011 Mar 25. PubMed PMID: 21438557. 5: Rouabhi R, Chagra A, Djebar-Berrebbah H, Djebar MR. The impact of flucycloxuron on eggs weight kinetic and hematological parameters of chicken (Gallus domesticus). Commun Agric Appl Biol Sci. 2007;72(2):143-50. PubMed PMID: 18399435. 6: Sun R, Lü M, Chen L, Li Q, Song H, Bi F, Huang R, Wang Q. Design, synthesis, bioactivity, and structure-activity relationship (SAR) studies of novel benzoylphenylureas containing oxime ether group. J Agric Food Chem. 2008 Dec 10;56(23):11376-91. doi: 10.1021/jf801901h. PubMed PMID: 18991456. 7: Qian M, Wu L, Zhang H, Xu M, Li R, Wang X, Sun C. Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry. Anal Bioanal Chem. 2012 Mar;402(7):2451-62. doi: 10.1007/s00216-011-5699-3. Epub 2012 Jan 20. PubMed PMID: 22271101. 8: Mommaerts V, Sterk G, Smagghe G. Hazards and uptake of chitin synthesis inhibitors in bumblebees Bombus terrestris. Pest Manag Sci. 2006 Aug;62(8):752-8. PubMed PMID: 16786494. 9: Van Leeuwen T, Van Pottelberge S, Tirry L. Comparative acaricide susceptibility and detoxifying enzyme activities in field-collected resistant and susceptible strains of Tetranychus urticae. Pest Manag Sci. 2005 May;61(5):499-507. PubMed PMID: 15657956. 10: Dommarco R, Santilio A, Fornarelli L, Rubbiani M. Simultaneous quantitative determination of thirteen urea pesticides at sub-ppb levels on a Zorbax SB-C18 column. J Chromatogr A. 1998 Nov 6;825(2):200-4. PubMed PMID: 9842721. 11: Moss SR. Herbicide-resistant weeds in Europe: the wider implications. Commun Agric Appl Biol Sci. 2004;69(3):3-11. PubMed PMID: 15759389.

View History

Flucloronide

Flucloronide