MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 571014 | Name: Mirosamicin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mirosamicin is a macrolide antibiotic that has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma. It has weak clastogenetic properties.

Chemical Structure

Mirosamicin
Mirosamicin
CAS#73684-69-2

Theoretical Analysis

MedKoo Cat#: 571014

Name: Mirosamicin

CAS#: 73684-69-2

Chemical Formula: C37H61NO13

Exact Mass: 727.4143

Molecular Weight: 727.89

Elemental Analysis: C, 61.05; H, 8.45; N, 1.92; O, 28.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Mirosamicin, A 11725 II, Antibiotic AR 5-2
IUPAC/Chemical Name
(1R,2S,3R,6E,8S,9S,10S,12R,14E,16S)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3-ethyl-2-hydroxy-2-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-8,10,12-trimethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione
InChi Key
WWIDEZOUVSJVHS-ZPQCYHEESA-N
InChi Code
InChI=1S/C37H61NO13/c1-11-27-37(43,18-46-36-33(45-10)32(44-9)29(41)23(6)48-36)34-26(49-34)14-13-25(39)20(3)16-21(4)31(19(2)12-15-28(40)50-27)51-35-30(42)24(38(7)8)17-22(5)47-35/h12-15,19-24,26-27,29-36,41-43H,11,16-18H2,1-10H3/b14-13+,15-12+/t19-,20+,21-,22+,23+,24-,26-,27+,29+,30+,31+,32+,33+,34+,35-,36+,37-/m0/s1
SMILES Code
CC[C@H]1OC(/C=C/[C@@H]([C@H]([C@H](C[C@H](C(/C=C/[C@@H]2O[C@H]2[C@@]1(CO[C@@H]3O[C@@H]([C@H]([C@H]([C@H]3OC)OC)O)C)O)=O)C)C)O[C@@H]4O[C@@H](C[C@H](N(C)C)[C@H]4O)C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 727.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakajima C, Sakogawa T, Okayama A, Nakamura A, Hayama T. Disposition of mirosamicin in honeybee hives. J Vet Pharmacol Ther. 1998 Aug;21(4):269-73. PubMed PMID: 9731948. 2: Horie M, Saito K, Ishii R, Yoshida T, Haramaki Y, Nakazawa H. Simultaneous determination of five macrolide antibiotics in meat by high-performance liquid chromatography. J Chromatogr A. 1998 Jul 3;812(1-2):295-302. PubMed PMID: 9691326. 3: Hayama T. [Pharmacological approach to control American foulbrood of honeybees]. Nihon Yakurigaku Zasshi. 1997 Oct;110(4):183-93. Review. Japanese. PubMed PMID: 9396023. 4: Horie M, Saito K, Nose N, Oka H, Nakazawa H. Determination of mirosamicin in animal tissues by high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 22;655(1):47-52. PubMed PMID: 8061833. 5: Sono A, Oyaide K, Suzuki A, Kobayashi Y, Matsumoto K, Yamamoto H. [Mutagenicity studies of miporamicin]. Jpn J Antibiot. 1989 Nov;42(11):2506-12. Japanese. PubMed PMID: 2621789. 6: Hazelden KP, Wilson JA, Sasaki M, Takahashi H, Yamamoto H. [Miporamicin teratogenicity study in rabbits]. Jpn J Antibiot. 1989 Nov;42(11):2488-99. Japanese. PubMed PMID: 2621787. 7: Kohira T, Nakanishi D, Goto I, Kobayashi Y, Matsumoto K, Yamamoto H. [Local irritation study of miporamicin in male rabbits]. Jpn J Antibiot. 1989 Nov;42(11):2513-25. Japanese. PubMed PMID: 2621790. 8: Motoyama K, Sumi A, Miura M, Yano J, Morino T, Matsumoto K, Yamamoto H. [Subacute toxicity study of miporamicin in rats by twenty-eight-day administration in feed]. Jpn J Antibiot. 1989 Nov;42(11):2422-46. Japanese. PubMed PMID: 2621784. 9: Sasaki M, Sano K, Sumi A, Motoyama K, Yano J, Matsumoto K, Yamamoto H. [Acute toxicity studies of miporamicin and its degradation products and metabolites in the mouse and rat]. Jpn J Antibiot. 1989 Nov;42(11):2412-21. Japanese. PubMed PMID: 2621783. 10: Nakano Y, Goto I, Kobayashi Y, Matsumoto K, Yamamoto H. [Studies on antigenicity and contact sensitivity of miporamicin]. Jpn J Antibiot. 1989 Nov;42(11):2500-5. Japanese. PubMed PMID: 2621788. 11: Furuhashi T, Suda H, Sasaki M, Nakajima M, Yamamoto H. [Oral dosage study of miporamicin administered during the period of fetal organogenesis in rats]. Jpn J Antibiot. 1989 Nov;42(11):2472-87. Japanese. PubMed PMID: 2621786. 12: Motoyama K, Sumi A, Miura M, Yano J, Morino T, Matsumoto K, Yamamoto H. [Six-month chronic toxicity study of miporamicin in rats]. Jpn J Antibiot. 1989 Nov;42(11):2447-71. Japanese. PubMed PMID: 2621785.

View History

Missourin

Missourin