MedKoo Cat#: 561166 | Name: EC-19

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EC-19 induce the differentiation of EC cells. EC-19 directs the cells to form epithelial-like derivatives.

Chemical Structure

EC-19
EC-19
CAS#1010694-08-2

Theoretical Analysis

MedKoo Cat#: 561166

Name: EC-19

CAS#: 1010694-08-2

Chemical Formula: C23H24O2

Exact Mass: 332.1776

Molecular Weight: 332.44

Elemental Analysis: C, 83.10; H, 7.28; O, 9.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
EC-19; EC19; EC 19
IUPAC/Chemical Name
3-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]benzoic acid
InChi Key
PMRFEKRJNZQOSY-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H24O2/c1-22(2)12-13-23(3,4)20-15-17(10-11-19(20)22)9-8-16-6-5-7-18(14-16)21(24)25/h5-7,10-11,14-15H,12-13H2,1-4H3,(H,24,25)
SMILES Code
O=C(O)C1=CC=CC(C#CC2=CC=C3C(C)(C)CCC(C)(C)C3=C2)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 332.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kurz SG, Hazra S, Bethel CR, Romagnoli C, Caselli E, Prati F, Blanchard JS, Bonomo RA. Inhibiting the β-Lactamase of Mycobacterium tuberculosis (Mtb) with Novel Boronic Acid Transition-State Inhibitors (BATSIs). ACS Infect Dis. 2015 Jun 12;1(6):234-42. doi: 10.1021/acsinfecdis.5b00003. Epub 2015 Apr 15. PubMed PMID: 27622739. 2: Lopez-Real RE, Budge JJ, Marder TB, Whiting A, Hunt PN, Przyborski SA. Application of synthetic photostable retinoids induces novel limb and facial phenotypes during chick embryogenesis in vivo. J Anat. 2014 Apr;224(4):392-411. doi: 10.1111/joa.12147. Epub 2013 Dec 4. Erratum in: J Anat. 2014 Apr;224(4):529. J Anat. 2014 Apr;224(4):529. PubMed PMID: 24303996; PubMed Central PMCID: PMC4098675. 3: Clemens G, Flower KR, Henderson AP, Whiting A, Przyborski SA, Jimenez-Hernandez M, Ball F, Bassan P, Cinque G, Gardner P. The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Mol Biosyst. 2013 Apr 5;9(4):677-92. doi: 10.1039/c3mb25505k. PubMed PMID: 23364809. 4: Beceiro A, Maharjan S, Gaulton T, Doumith M, Soares NC, Dhanji H, Warner M, Doyle M, Hickey M, Downie G, Bou G, Livermore DM, Woodford N. False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins. J Antimicrob Chemother. 2011 Sep;66(9):2006-10. doi: 10.1093/jac/dkr265. Epub 2011 Jul 8. PubMed PMID: 21742679. 5: Maltman DJ, Christie VB, Collings JC, Barnard JH, Fenyk S, Marder TB, Whiting A, Przyborski SA. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst. 2009 May;5(5):458-71. doi: 10.1039/b817912c. Epub 2009 Mar 12. PubMed PMID: 19381361. 6: Williams DR, Kiryanov AA, Emde U, Clark MP, Berliner MA, Reeves JT. Studies of stereocontrolled allylation reactions for the total synthesis of phorboxazole A. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12058-63. Epub 2004 Jul 26. PubMed PMID: 15277662; PubMed Central PMCID: PMC514434.