PA1 2HCl is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 2HCl enables the optical control of ENaC channels, in particular the δβγ isoform, by switching between blue and green light, or by turning on and off blue light. PA1 2HCl was used to modify functionally δβγENaC in amphibian and mammalian cells.
MedKoo Cat#: 561161
Name: PA1 2HCl
CAS#: 1620951-72-5 (free base)
Chemical Formula: C18H18Cl3N9O
Exact Mass:
Molecular Weight: 482.75
Elemental Analysis: C, 44.78; H, 3.76; Cl, 22.03; N, 26.11; O, 3.31
The following data is based on the product molecular weight 482.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
