MedKoo Cat#: 561158 | Name: AS-8351
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AS-8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.

Chemical Structure

AS-8351
AS-8351
CAS#796-42-9

Theoretical Analysis

MedKoo Cat#: 561158

Name: AS-8351

CAS#: 796-42-9

Chemical Formula: C17H13N3O2

Exact Mass: 291.1008

Molecular Weight: 291.31

Elemental Analysis: C, 70.09; H, 4.50; N, 14.42; O, 10.98

Price and Availability

Size Price Availability Quantity
25mg USD 250.00 2 Weeks
50mg USD 400.00 2 Weeks
100mg USD 650.00 2 Weeks
200mg USD 950.00 2 Weeks
500mg USD 1,650.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 4,850.00 2 Weeks
5g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
AS-8351; AS8351; AS 8351
IUPAC/Chemical Name
2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone
InChi Key
WQSHHAVECQJKLX-YBFXNURJSA-N
InChi Code
InChI=1S/C17H13N3O2/c21-16-6-5-12-3-1-2-4-14(12)15(16)11-19-20-17(22)13-7-9-18-10-8-13/h1-11,21H,(H,20,22)/b19-11+
SMILES Code
OC1=CC=C2C=CC=CC2=C1/C=N/NC(C3=CC=NC=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu JD, Nie B, Xie M, Zhang M, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S. Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science. 2016 Jun 3;352(6290):1216-20. doi: 10.1126/science.aaf1502. Epub 2016 Apr 28. PubMed PMID: 27127239.