IQ-R | CAS#1345445-57-9 | fluorescent probe

MedKoo Cat#: 561149 | Name: IQ-R

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IQ-R is a hypoxia-sensitive fluorescent probe. IQ-R has good solubility in water and longer wavelength for absorption and emission, which are favorable for cellular bioimaging.

Chemical Structure

IQ-R

CAS#1345445-57-9

Theoretical Analysis

MedKoo Cat#: 561149

Name: IQ-R

CAS#: 1345445-57-9

Chemical Formula: C34H28N2O7

Exact Mass: 576.1897

Molecular Weight: 576.61

Elemental Analysis: C, 70.82; H, 4.89; N, 4.86; O, 19.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

IQ-R; IQ R; IQR

IUPAC/Chemical Name

2-(6-Dimethylamino-3-oxo-3H-xanthen-9-yl)-benzoic acid 5-methoxy-1,2-dimethyl-4,7-dioxo-4,7-dihydro-1H-indol-3-ylmethyl ester

InChi Key

XAVOZQBGUYUYJD-UHFFFAOYSA-N

InChi Code

InChI=1S/C34H28N2O7/c1-18-25(31-32(36(18)4)26(38)16-29(41-5)33(31)39)17-42-34(40)22-9-7-6-8-21(22)30-23-12-10-19(35(2)3)14-27(23)43-28-15-20(37)11-13-24(28)30/h6-16H,17H2,1-5H3

SMILES Code

O=C(OCC1=C(C)N(C)C2=C1C(C(OC)=CC2=O)=O)C3=CC=CC=C3C4=C5C=CC(C=C5OC6=C4C=CC(N(C)C)=C6)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 576.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hirokazu Komatsu, Hiroshi Harada, Kazuhito Tanabe, Masahiro Hiraokad, Sei-ichi Nishimoto. Indolequinone-rhodol conjugate as a fluorescent probe for hypoxic cells: enzymatic activation and fluorescence properties.