HQ-415 | CS#430462-93-4 | metal chelator

MedKoo Cat#: 561100 | Name: HQ-415

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HQ-415 is a clinically relevant bioactive metal chelator.

Chemical Structure

HQ-415

CAS#430462-93-4

Theoretical Analysis

MedKoo Cat#: 561100

Name: HQ-415

CAS#: 430462-93-4

Chemical Formula: C25H25N3O3

Exact Mass: 415.1896

Molecular Weight: 415.49

Elemental Analysis: C, 72.27; H, 6.07; N, 10.11; O, 11.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HQ-415; HQ 415; HQ415

IUPAC/Chemical Name

7-[(3-Ethoxy-4-methoxyphenyl)-[(4-methylpyridin-2-yl)amino]methyl]quinolin-8-ol

InChi Key

ZUOOFZJZQYFZQW-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H25N3O3/c1-4-31-21-15-18(8-10-20(21)30-3)23(28-22-14-16(2)11-13-26-22)19-9-7-17-6-5-12-27-24(17)25(19)29/h5-15,23,29H,4H2,1-3H3,(H,26,28)

SMILES Code

OC1=C2N=CC=CC2=CC=C1C(C3=CC=C(OC)C(OCC)=C3)NC4=NC=CC(C)=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 415.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tardiff DF, Tucci ML, Caldwell KA, Caldwell GA, Lindquist S. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. J Biol Chem. 2012 Feb 3;287(6):4107-20. doi: 10.1074/jbc.M111.308668. Epub 2011 Dec 6. PubMed PMID: 22147697; PubMed Central PMCID: PMC3281691.