MDK-2959 | CAS#577962-95-9 | PTPsigma inhibitor

MedKoo Cat#: 561094 | Name: MDK-2959

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDK-2959, also known as PTPsigma inhibitor 2, is a potent inhibitor of protein tyrosine phosphatase sigma (PTPsigma). The last four digits of MDK-2959's CAS# are used in its name.

Chemical Structure

MDK-2959

CAS#577962-95-9

Theoretical Analysis

MedKoo Cat#: 561094

Name: MDK-2959

CAS#: 577962-95-9

Chemical Formula: C15H11N3O4

Exact Mass: 297.0750

Molecular Weight: 297.27

Elemental Analysis: C, 60.61; H, 3.73; N, 14.14; O, 21.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MDK-2959; MDK2959; MDK 2959; PTPsigma inhibitor 2; PTPsigma inhibitor2; PTPsigmainhibitor2

IUPAC/Chemical Name

(E)-4-[2-(2,5-Dioxo-imidazolidin-4-ylidenemethyl)-pyrrol-1-yl]-benzoic acid

InChi Key

WMOKBKUDIRNAKD-XYOKQWHBSA-N

InChi Code

InChI=1S/C15H11N3O4/c19-13-12(16-15(22)17-13)8-11-2-1-7-18(11)10-5-3-9(4-6-10)14(20)21/h1-8H,(H,20,21)(H2,16,17,19,22)/b12-8+

SMILES Code

O=C(O)C1=CC=C(N2C(/C=C(C(N3)=O)/NC3=O)=CC=C2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 297.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Park H, Chien PN, Ryu SE. Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6333-7. doi: 10.1016/j.bmcl.2012.08.081. Epub 2012 Aug 29. PubMed PMID: 22989533.