G-Glu-Val | CAS#2746-34-1 | dipeptide

MedKoo Cat#: 561069 | Name: G-Glu-Val

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

G-Glu-Val, also known as gamma-Glutamyl-L-valine or H-gGlu-Val-OH, is a taste-modulating dipeptide and a main contributor to the "kokumi" taste of edible beans.

Chemical Structure

G-Glu-Val

CAS#2746-34-1

Theoretical Analysis

MedKoo Cat#: 561069

Name: G-Glu-Val

CAS#: 2746-34-1

Chemical Formula: C10H18N2O5

Exact Mass: 246.1216

Molecular Weight: 246.26

Elemental Analysis: C, 48.77; H, 7.37; N, 11.38; O, 32.48

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 250.00	2 Weeks
1g	USD 650.00	2 Weeks

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Related CAS #

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Synonym

G-Glu-Val; gamma-Glu-Val; gamma-glutamylvaline; g-Glutamylvaline; gamma-L-Glu-L-val; L-g-Glu-L-val; H-Glu(Val-OH)-OH

IUPAC/Chemical Name

(2S)-2-Amino-5-[[(1S)-1-carboxy-2-methylpropyl]amino]-5-oxopentanoic acid

InChi Key

AQAKHZVPOOGUCK-XPUUQOCRSA-N

InChi Code

InChI=1S/C10H18N2O5/c1-5(2)8(10(16)17)12-7(13)4-3-6(11)9(14)15/h5-6,8H,3-4,11H2,1-2H3,(H,12,13)(H,14,15)(H,16,17)/t6-,8-/m0/s1

SMILES Code

O=C(O)[C@@H](N)CCC(N[C@H](C(O)=O)C(C)C)=O

Appearance

Solid powder

Purity

>97% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

G-Glu-Val, also known as gamma-Glutamyl-L-valine or H-gGlu-Val-OH, is a taste-modulating dipeptide.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 246.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Dunkel A, Köster J, Hofmann T. Molecular and sensory characterization of gamma-glutamyl peptides as key contributors to the kokumi taste of edible beans (Phaseolus vulgaris L.). J Agric Food Chem. 2007 Aug 8;55(16):6712-9. Epub 2007 Jul 7. PubMed PMID: 17616213. 2: Suzuki H, Kato K, Kumagai H. Enzymatic synthesis of gamma-glutamylvaline to improve the bitter taste of valine. J Agric Food Chem. 2004 Feb 11;52(3):577-80. PubMed PMID: 14759151. 3: Toelstede S, Dunkel A, Hofmann T. A series of kokumi peptides impart the long-lasting mouthfulness of matured Gouda cheese. J Agric Food Chem. 2009 Feb 25;57(4):1440-8. doi: 10.1021/jf803376d. PubMed PMID: 19170504. 4: Toelstede S, Hofmann T. Kokumi-active glutamyl peptides in cheeses and their biogeneration by Penicillium roquefortii. J Agric Food Chem. 2009 May 13;57(9):3738-48. doi: 10.1021/jf900280j. PubMed PMID: 19338275. 5: Hillmann H, Hofmann T. Quantitation of Key Tastants and Re-engineering the Taste of Parmesan Cheese. J Agric Food Chem. 2016 Mar 2;64(8):1794-805. doi: 10.1021/acs.jafc.6b00112. Epub 2016 Feb 18. PubMed PMID: 26870875.