Related CAS #
534-73-6 (Isomaltitol)
64519-82-0 (Palatinit)
Synonym
Isomaltitol; Palatinit; Isomalt
IUPAC/Chemical Name
(2S,3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol
InChi Key
SERLAGPUMNYUCK-YJOKQAJESA-N
InChi Code
InChI=1S/C12H24O11/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12/h4-21H,1-3H2/t4-,5+,6+,7+,8+,9+,10-,11+,12-/m0/s1
SMILES Code
OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
344.31
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Schröder S, Kröger L, Mattes R, Thiem J. Transglycosylations employing recombinant α- and β-galactosidases and novel donor substrates. Carbohydr Res. 2015 Feb 11;403:157-66. doi: 10.1016/j.carres.2014.05.005. Epub 2014 May 20. PubMed PMID: 24909380.
3: Evaldsson C, Rydén I, Uppugunduri S. Isomaltitol exacerbates neutrophilia but reduces eosinophilia: new insights into the sephadex model of lung inflammation. Int Arch Allergy Immunol. 2011;154(4):286-94. doi: 10.1159/000321820. Epub 2010 Oct 20. PubMed PMID: 20962533.
4: Uppugunduri S, Gautam C. Effects of uridine, isomatitol and 4-thiouridine on in vitro cell adhesion and in vivo effects of 4-thiouridine in a lung inflammation model. Int Immunopharmacol. 2004 Sep;4(9):1241-8. PubMed PMID: 15251120.
5: Cataldi TR, Campa C, Casella IG, Bufo SA. Determination of maltitol, isomaltitol, and lactitol by high-pH anion-exchange chromatography with pulsed amperometric detection. J Agric Food Chem. 1999 Jan;47(1):157-63. PubMed PMID: 10563865.
6: Smits-Van Prooije AE, De Groot AP, Dreef-Van der Meulen HC, Sinkeldam EJ. Chronic toxicity and carcinogenicity study of isomalt in rats and mice. Food Chem Toxicol. 1990 Apr;28(4):243-51. PubMed PMID: 2358250.
7: Rosiers C, Verwaerde F, Dupas H, Bouquelet S. New approach to the metabolism of hydrogenated starch hydrolysate: hydrolysis by the maltase/glucoamylase complex of the rat intestinal mucosa. Ann Nutr Metab. 1985;29(2):76-82. PubMed PMID: 3922278.
8: Ziesenitz SC. Bioavailability of glucose from Palatinit. Z Ernahrungswiss. 1983 Sep;22(3):185-94. PubMed PMID: 6417920.
9: Siebert G, Grupp U, Heinkel K. Studies on isomaltitol. Nutr Metab. 1975;18 Suppl 1:191-6. PubMed PMID: 1165864.
10: Musch K, Siebert G, Schiweck H, Steinle G. [Nutritional physiology of isomaltitol in the rat]. Z Ernahrungswiss Suppl. 1973;15:3-16. German. PubMed PMID: 4518248.
11: Gehring F. [Formation of acids by cariogenically important streptococci from sugars and sugar alcohols with special reference to isomaltitol and isomaltulose]. Z Ernahrungswiss Suppl. 1973;15:16-27. German. PubMed PMID: 4518246.
