MedKoo Cat#: 561002 | Name: SB2602

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB2602 is a selective mTOR inhibitor.

Chemical Structure

SB2602
SB2602
CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 561002

Name: SB2602

CAS#: Unknown

Chemical Formula: C20H26N8O

Exact Mass: 394.2230

Molecular Weight: 394.48

Elemental Analysis: C, 60.89; H, 6.64; N, 28.41; O, 4.06

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SB2602; SB-2602; SB 2602.
IUPAC/Chemical Name
5-[9-(1-Ethyl-propyl)-2-(3-oxa-8-aza-bicyclo[3.2.1]oct-8-yl)-9H-purin-6-yl]-pyrimidin-2-ylamine
InChi Key
CSXIBRFMHYJETC-GICMACPYSA-N
InChi Code
InChI=1S/C20H26N8O/c1-3-13(4-2)27-11-24-17-16(12-7-22-19(21)23-8-12)25-20(26-18(17)27)28-14-5-6-15(28)10-29-9-14/h7-8,11,13-15H,3-6,9-10H2,1-2H3,(H2,21,22,23)/t14-,15?/m1/s1
SMILES Code
NC1=NC=C(C2=C3N=CN(C(CC)CC)C3=NC(N4[C@H]5COCC4CC5)=N2)C=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 394.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Poulsen A, Nagaraj H, Lee A, Blanchard S, Soh CK, Chen D, Wang H, Hart S, Goh KC, Dymock B, Williams M. Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602. J Chem Inf Model. 2014 Nov 24;54(11):3238-50. doi: 10.1021/ci500493m. Epub 2014 Oct 23. PubMed PMID: 25317974.