MedKoo Cat#: 551027 | Name: YKAs3003

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YKAs3003 is a novel potent inhibitor of pathogenic KAS III. This antimicrobial compound displays minimal inhibitory concentration (MIC) values in the range 128-256 microg/mL against various bacteria.

Chemical Structure

YKAs3003
YKAs3003
CAS#329180-48-5

Theoretical Analysis

MedKoo Cat#: 551027

Name: YKAs3003

CAS#: 329180-48-5

Chemical Formula: C13H17NO2

Exact Mass: 219.1259

Molecular Weight: 219.28

Elemental Analysis: C, 71.21; H, 7.81; N, 6.39; O, 14.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
YKAs3003; YKAs-3003; YKAs3003
IUPAC/Chemical Name
4-Cyclohexyliminomethyl-benzene-1,3-diol
InChi Key
UGMBMYJAUTUEJB-NTEUORMPSA-N
InChi Code
InChI=1S/C13H17NO2/c15-12-7-6-10(13(16)8-12)9-14-11-4-2-1-3-5-11/h6-9,11,15-16H,1-5H2/b14-9+
SMILES Code
OC1=CC=C(/C=N/C2CCCCC2)C(O)=C1
Appearance
White to off-white solid powder.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 219.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lee JY, Jeong KW, Shin S, Lee JU, Kim Y. Discovery of novel selective inhibitors of Staphylococcus aureus β-ketoacyl acyl carrier protein synthase III. Eur J Med Chem. 2012 Jan;47(1):261-9. doi: 10.1016/j.ejmech.2011.10.052. Epub 2011 Nov 4. PubMed PMID: 22104972. 2: Lee JY, Jeong KW, Lee JU, Kang DI, Kim Y. Novel E. coli beta-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics. Bioorg Med Chem. 2009 Feb 15;17(4):1506-13. doi: 10.1016/j.bmc.2009.01.004. Epub 2009 Jan 11. PubMed PMID: 19185501.