SNS062-analog is a non-covalently binding inhibitor of Bruton's tyrosine kinase (BTK). SNS062-analog was mistakenly listed and sold as SNS-062 by some reagent suppliers. SNS062-analog was reported in patent WO 2011029043 (Sunesis Pharmaceuticals). SNS062-analog showed IC50 of <100 nM, against Bruton's tyrosine kinase (Btk kinase). NOTE: SNS-062 (also known as Vecabrutinib, CAT#561137) is a clinical stage drug candidate.
MedKoo Cat#: 206844
Name: SNS062 analog
CAS#: 1270014-40-8 (SNS062 analog)
Chemical Formula: C19H21ClN6O
Exact Mass: 384.1465
Molecular Weight: 384.87
Elemental Analysis: C, 59.30; H, 5.50; Cl, 9.21; N, 21.84; O, 4.16
The following data is based on the product molecular weight 384.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
