MedKoo Cat#: 526290 | Name: PDD-00017273
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PDD-00017273 is a novel potent and selective poly(ADP-ribose)glycohydrolase (PARG) inhibitor.

Chemical Structure

PDD-00017273
PDD-00017273
CAS#1945950-21-9

Theoretical Analysis

MedKoo Cat#: 526290

Name: PDD-00017273

CAS#: 1945950-21-9

Chemical Formula: C23H26N6O4S2

Exact Mass: 514.1457

Molecular Weight: 514.62

Elemental Analysis: C, 53.68; H, 5.09; N, 16.33; O, 12.44; S, 12.46

Price and Availability

Size Price Availability Quantity
5mg USD 450.00
25mg USD 850.00
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Related CAS #
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Synonym
PDD-00017273; PDD 00017273; PDD00017273; PDD-17273; PDD 17273; PDD 17273;
IUPAC/Chemical Name
1-[(1,3-Dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide
InChi Key
IFWUBRBMMNTBRZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H26N6O4S2/c1-14-9-16(27(4)25-14)12-28-20-6-5-18(35(32,33)26-23(3)7-8-23)10-19(20)21(30)29(22(28)31)13-17-11-24-15(2)34-17/h5-6,9-11,26H,7-8,12-13H2,1-4H3
SMILES Code
O=S(C1=CC2=C(N(CC3=CC(C)=NN3C)C(N(CC4=CN=C(C)S4)C2=O)=O)C=C1)(NC5(C)CC5)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 514.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Puentes, L. N., Lengyel-Zhand, Z., Lee, J. Y., Hsieh, C. J., Schneider Jr, M. E., Edwards, K. J., ... & Mach, R. H. (2021). Poly (ADP-ribose) interacts with phosphorylated α-synuclein in post mortem PD samples. Frontiers in Aging Neuroscience, 13, 704041.