Beta-blocker-15 is a novel negative allosteric modulator of the ß2-adrenergic receptor (ß2AR), inhibiting cAMP production through the ß2AR, but not that mediated by other Gs-coupled receptors, also inhibiting ß-arrestin recruitment to the activated ß2AR.
MedKoo Cat#: 525968
Name: Beta-blocker-15
CAS#: N/A
Chemical Formula: C34H39BrN4O4
Exact Mass: 646.2155
Molecular Weight: 647.61
Elemental Analysis: C, 63.06; H, 6.07; Br, 12.34; N, 8.65; O, 9.88
The following data is based on the product molecular weight 647.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
