IUPAC/Chemical Name
N,N'-1,2-Ethanediylbis[2-(9H-xanthen-9-ylthio)-propanamide]
InChi Key
KBXOGBYQKMAAIA-UHFFFAOYSA-N
InChi Code
InChI=1S/C34H32N2O4S2/c1-21(41-31-23-11-3-7-15-27(23)39-28-16-8-4-12-24(28)31)33(37)35-19-20-36-34(38)22(2)42-32-25-13-5-9-17-29(25)40-30-18-10-6-14-26(30)32/h3-18,21-22,31-32H,19-20H2,1-2H3,(H,35,37)(H,36,38)
SMILES Code
CC(SC1C2=C(OC3=C1C=CC=C3)C=CC=C2)C(NCCNC(C(SC4C5=C(OC6=C4C=CC=C6)C=CC=C5)C)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
596.76
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Ben-Gera J, Klement E, Khinich E, Stram Y, Shpigel NY. Comparison of the efficacy of Neethling lumpy skin disease virus and x10RM65 sheep-pox live attenuated vaccines for the prevention of lumpy skin disease - The results of a randomized controlled field study. Vaccine. 2015 Sep 11;33(38):4837-42. doi: 10.1016/j.vaccine.2015.07.071. Epub 2015 Aug 1. PubMed PMID: 26238726.
2: Abutarbush SM, Hananeh WM, Ramadan W, Al Sheyab OM, Alnajjar AR, Al Zoubi IG, Knowles NJ, Bachanek-Bankowska K, Tuppurainen ES. Adverse Reactions to Field Vaccination Against Lumpy Skin Disease in Jordan. Transbound Emerg Dis. 2016 Apr;63(2):e213-9. doi: 10.1111/tbed.12257. Epub 2014 Aug 6. PubMed PMID: 25098267.
3: Brenner J, Bellaiche M, Gross E, Elad D, Oved Z, Haimovitz M, Wasserman A, Friedgut O, Stram Y, Bumbarov V, Yadin H. Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge. Vaccine. 2009 Mar 4;27(10):1500-3. doi: 10.1016/j.vaccine.2009.01.020. Epub 2009 Jan 30. PubMed PMID: 19186204.
4: Spannhoff A, Machmur R, Heinke R, Trojer P, Bauer I, Brosch G, Schüle R, Hanefeld W, Sippl W, Jung M. A novel arginine methyltransferase inhibitor with cellular activity. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4150-3. Epub 2007 Jun 3. PubMed PMID: 17570663.
5: Fassi-Fehri M, El-Harrak M, Johnson D, Abbadi M, El-Idrissi AH. [Experimental study of postvaccinal immunity to sheep-pox]. Ann Rech Vet. 1984;15(1):59-64. French. PubMed PMID: 6091523.
