MedKoo Cat#: 532962 | Name: WAY 207024 dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WAY 207024 dihydrochloride is a gonadotropin releasing hormone receptor (GnRH-R) antagonist. WAY 207024 dihydrochloride exhibits potent affinity (IC50 values are 12 and 71 nM for human and rat GnRH receptors respectively).

Chemical Structure

WAY 207024 dihydrochloride
WAY 207024 dihydrochloride
CAS#872002-73-8

Theoretical Analysis

MedKoo Cat#: 532962

Name: WAY 207024 dihydrochloride

CAS#: 872002-73-8

Chemical Formula: C30H34Cl2N6

Exact Mass:

Molecular Weight: 549.54

Elemental Analysis: C, 65.57; H, 6.24; Cl, 12.90; N, 15.29

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
872002-73-8 (2HCl) 872002-72-7 (free)
Synonym
WAY-207024 ; WAY 207024 ; WAY207024; WAY 207024 dihydrochloride; WAY 207024 diHCl.
IUPAC/Chemical Name
6-((4-(2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazol-4-yl)piperazin-1-yl)methyl)quinoxaline dihydrochloride
InChi Key
REQCNTGYEABOIT-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H32N6.2ClH/c1-30(2,3)23-10-8-22(9-11-23)29-33-25-5-4-6-27(28(25)34-29)36-17-15-35(16-18-36)20-21-7-12-24-26(19-21)32-14-13-31-24;;/h4-14,19H,15-18,20H2,1-3H3,(H,33,34);2*1H
SMILES Code
CC(C1=CC=C(C2=NC3=C(N4CCN(CC5=CC=C6N=CC=NC6=C5)CC4)C=CC=C3N2)C=C1)(C)C.[H]Cl.[H]Cl
Appearance
White to off-white solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 549.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pelletier JC, Chengalvala MV, Cottom JE, Feingold IB, Green DM, Hauze DB, Huselton CA, Jetter JW, Kopf GS, Lundquist JT, Magolda RL, Mann CW, Mehlmann JF, Rogers JF, Shanno LK, Adams WR, Tio CO, Wrobel JE. Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxal ine (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R). J Med Chem. 2009 Apr 9;52(7):2148-52. doi: 10.1021/jm801572m. PubMed PMID: 19271735.