STK899704 is a novel tubulin inhibitor, preventing the polymerization of purified tubulin in vitro and depolymerizing microtubule in cultured cells leading to mitotic arrest, associated with increased Cdc25C phosphorylation and the accumulation of both cyclin B1 and polo-like kinase 1 (Plk1), and apoptosis.
MedKoo Cat#: 525431
Name: STK899704
CAS#: 371135-20-5
Chemical Formula: C27H23N3O4
Exact Mass: 453.1689
Molecular Weight: 453.50
Elemental Analysis: C, 71.51; H, 5.11; N, 9.27; O, 14.11
The following data is based on the product molecular weight 453.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
