PF-122 is a novel potent inhibitor of Bruton's tyrosine kinase (BTK), blocking both B-cell receptor and FcR-mediated signaling, and preventing FcR-dependent, antibody-mediated proteinuria in a mouse glomerulonephritis model.
MedKoo Cat#: 525364
Name: PF-122
CAS#: N/A
Chemical Formula: C22H20F2N6O2
Exact Mass: 438.1616
Molecular Weight: 438.44
Elemental Analysis: C, 60.27; H, 4.60; F, 8.67; N, 19.17; O, 7.30
The following data is based on the product molecular weight 438.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
