Ponfibrate | CAS#53341-49-4

MedKoo Cat#: 525357 | Name: Ponfibrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ponfibrate is a hypobetalipoproteinemic and Lipid decreasing agent.

Chemical Structure

Ponfibrate

CAS#53341-49-4

Theoretical Analysis

MedKoo Cat#: 525357

Name: Ponfibrate

CAS#: 53341-49-4

Chemical Formula: C18H18Cl2O4

Exact Mass: 368.0582

Molecular Weight: 369.24

Elemental Analysis: C, 58.55; H, 4.91; Cl, 19.20; O, 17.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Ponfibrate

IUPAC/Chemical Name

Ethyl trans-3,7-dichloro-5-methyl-5H-benzo[d][1,3]benzodioxocine-11-carboxylate

InChi Key

CTRIHNQYAJUZTQ-OQLLNIDSSA-N

InChi Code

InChI=1S/C18H18Cl2O4/c1-3-22-18(21)14-5-4-6-16-15(14)9-12-7-8-13(19)10-17(12)23(2)11-24(16)20/h4-10,16H,3,11H2,1-2H3/b15-9+

SMILES Code

O=C(C1=CC=CC2O(Cl)CO(C)C3=CC(Cl)=CC=C3/C=C2\1)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 369.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nichols GA, Koro CE, Chan W, Bowlin SJ, Sprecher DL. The association between fibrate use, change in high-density lipoprotein cholesterol, and the risk of cardiovascular disease: a retrospective chart review involving up to 8 years of follow-up. Clin Ther. 2006 Feb;28(2):243-50. PubMed PMID: 16678645. 2: Yang CC, Jick SS, Testa MA. Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics. Br J Clin Pharmacol. 2003 Jul;56(1):84-91. PubMed PMID: 12848779; PubMed Central PMCID: PMC1884321. 3: Balfour JA, McTavish D, Heel RC. Fenofibrate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia. Drugs. 1990 Aug;40(2):260-90. Review. PubMed PMID: 2226216.