UNC0006 is a β-arrestin-biased dopamine D2 ligand for probing signal transduction pathways essential for antipsychotic efficacy. Elucidating the key signal transduction pathways essential for both antipsychotic efficacy and side-effect profiles is essential for developing safer and more effective therapies. Noncanonical modes of dopamine D(2) receptor (D(2)R) signaling via β-arrestins are important for the therapeutic actions of both antipsychotic and antimanic agents
MedKoo Cat#: 530644
Name: UNC0006
CAS#: 1354030-14-0
Chemical Formula: C24H29Cl2N3O2
Exact Mass: 461.1637
Molecular Weight: 462.42
Elemental Analysis: C, 62.34; H, 6.32; Cl, 15.33; N, 9.09; O, 6.92
The following data is based on the product molecular weight 462.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
