BH3I-2' is a cell-permeable BH3 mimetic which induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bak BH3 and Bcl-x by targeting the Bcl-x binding pocket.
MedKoo Cat#: 525204
Name: BH3I-2'
CAS#: 315195-18-7
Chemical Formula: C19H11Cl3INO4S
Exact Mass: 580.8519
Molecular Weight: 582.61
Elemental Analysis: C, 39.17; H, 1.90; Cl, 18.25; I, 21.78; N, 2.40; O, 10.98; S, 5.50
The following data is based on the product molecular weight 582.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
