SC-53116 HCl hydrate | CAS# 879208-42-1 | 5-HT4 agonist

MedKoo Cat#: 532688 | Name: SC-53116 HCl hydrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SC-53116 HCl hydrate is a first selective agonist at the newly identified serotonin 5-HT4 receptor subtype.

Chemical Structure

SC-53116 HCl hydrate

CAS#879208-42-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 532688

Name: SC-53116 HCl hydrate

CAS#: 879208-42-1 (HCl)

Chemical Formula: C16H25Cl2N3O3

Exact Mass: 377.1273

Molecular Weight: 378.29

Elemental Analysis: C, 50.80; H, 6.66; Cl, 18.74; N, 11.11; O, 12.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

141196-99-8 (free base)

Synonym

SC-53116 hydrochloride hydrate; SC-53116 HCl hydrate

IUPAC/Chemical Name

4-Amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide Hydrochloride Hydrate

InChi Key

CZXMPKPHHWPFSI-UROSVOJDSA-N

InChi Code

InChI=1S/C16H22ClN3O2.ClH.H2O/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20;;/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21);1H;1H2/t10-,14-;;/m0../s1

SMILES Code

O=C(NC[C@H]1[C@]2([H])CCCN2CC1)C3=CC(Cl)=C(N)C=C3OC.[H]Cl.[H]O[H]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 378.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Becker DP, Flynn DL, Villamil CI. Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3073-5. PubMed PMID: 15149647. 2: Flynn DL, Zabrowski DL, Becker DP, Nosal R, Villamil CI, Gullikson GW, Moummi C, Yang DC. SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype. J Med Chem. 1992 Apr 17;35(8):1486-9. PubMed PMID: 1573641.