MedKoo Cat#: 532672 | Name: SB-611812

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB-611812 is a urotensin-II (UT) antagonist. It inhibits urotensin-II-induced proliferation of neonatal cardiac fibroblasts.

Chemical Structure

SB-611812
SB-611812
CAS#345892-71-9

Theoretical Analysis

MedKoo Cat#: 532672

Name: SB-611812

CAS#: 345892-71-9

Chemical Formula: C17H16Cl3F3N2O3S

Exact Mass: 489.9899

Molecular Weight: 491.73

Elemental Analysis: C, 41.52; H, 3.28; Cl, 21.63; F, 11.59; N, 5.70; O, 9.76; S, 6.52

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
SB-611812; SB 611812; SB611812; T23323; T-23323; T 23323;
IUPAC/Chemical Name
2,6-dichloro-N-[4-chloro-3-(2-dimethylaminoethoxy)phenyl]-4-(trifluoromethyl)benzenesulfonamide
InChi Key
UIZHOFJFIOCYLH-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16Cl3F3N2O3S/c1-25(2)5-6-28-15-9-11(3-4-12(15)18)24-29(26,27)16-13(19)7-10(8-14(16)20)17(21,22)23/h3-4,7-9,24H,5-6H2,1-2H3
SMILES Code
O=S(C1=C(Cl)C=C(C(F)(F)F)C=C1Cl)(NC2=CC=C(Cl)C(OCCN(C)C)=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 491.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Desai N, Sajjad J, Frishman WH. Urotensin II: a new pharmacologic target in the treatment of cardiovascular disease. Cardiol Rev. 2008 May-Jun;16(3):142-53. doi: 10.1097/CRD.0b013e31815c8048. Review. PubMed PMID: 18414185. 2: Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91. Review. PubMed PMID: 18473773.