MDK6664, also known as LPA2-IN-1 or LPA2 antagonist 1, is a potent LPA2 antagonist with IC50 17 nM in vitro for inhibition of LPA(2) mediated Erk activation and proliferation of HCT-116 cells. Lysophosphatidic acid (LPA) acts via binding to specific G protein-coupled receptors and has been implicated in the biology of breast cancer.
MedKoo Cat#: 407478
Name: MDK6664
CAS#: 1017606-66-4
Chemical Formula: C20H23Cl2N5O2S2
Exact Mass: 499.0670
Molecular Weight: 500.46
Elemental Analysis: C, 48.00; H, 4.63; Cl, 14.17; N, 13.99; O, 6.39; S, 12.81
The following data is based on the product molecular weight 500.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
