RS 17053 HCl | CAS#169505-93-5|α1A-adrenoceptor antagonist

MedKoo Cat#: 532585 | Name: RS 17053

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

RS 17053 HCl is a α1A-adrenoceptor antagonist, with very high affinity for α1A receptors (pKi and pA2 estimates of 9.1 - 9.9) and a 30 - 100 fold selectivity over the α1B and α1D subtypes (pKi and pA2 estimates 7.7 - 7.8).

Chemical Structure

RS 17053

CAS#169505-93-5

Theoretical Analysis

MedKoo Cat#: 532585

Name: RS 17053

CAS#: 169505-93-5

Chemical Formula: C24H30Cl2N2O2

Exact Mass: 0.0000

Molecular Weight: 449.42

Elemental Analysis: C, 64.14; H, 6.73; Cl, 15.78; N, 6.23; O, 7.12

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 350.00	2 Weeks
10mg	USD 550.00	2 Weeks

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Related CAS #

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Synonym

RS 17053 HCl; RS 17053 HCl; RS17053; RS-17053.

IUPAC/Chemical Name

(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine) hydrochloride

InChi Key

QFOPFGRPNPCPBX-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H29ClN2O2.ClH/c1-24(2,14-18-15-26-21-10-9-19(25)13-20(18)21)27-11-12-28-22-5-3-4-6-23(22)29-16-17-7-8-17;/h3-6,9-10,13,15,17,26-27H,7-8,11-12,14,16H2,1-2H3;1H

SMILES Code

CC(NCCOC1=CC=CC=C1OCC2CC2)(C)CC3=CNC4=C3C=C(Cl)C=C4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 449.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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