PSN375963 is a potent and selective agonist of GPR119 that shows similar potency to oleoyl ethanolamide (OEA) at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 8.4 and 7.9 µM, respectively (EC50 values for OEA are 3.2 and 2.9 µM, respectively). PSN375963 suggests that PSN375963 may be useful as a therapeutic agent for the treatment of obesity.
MedKoo Cat#: 532483
Name: PSN375963
CAS#: 388575-52-8
Chemical Formula: C17H23N3O
Exact Mass: 285.1841
Molecular Weight: 285.39
Elemental Analysis: C, 71.55; H, 8.12; N, 14.72; O, 5.61
The following data is based on the product molecular weight 285.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
