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MedKoo Cat#: 532468 | Name: PF-592379

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF-592379 a potent, selective agonist of the dopamine 3 receptor, for the treatment of male erectile dysfunction and female sexual dysfunction.

Chemical Structure

PF-592379
PF-592379
CAS#NA

Theoretical Analysis

MedKoo Cat#: 532468

Name: PF-592379

CAS#: NA

Chemical Formula: C13H21N3O

Exact Mass: 235.1685

Molecular Weight: 235.33

Elemental Analysis: C, 66.35; H, 8.99; N, 17.86; O, 6.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
PF-592379; PF 592379; PF592379.
IUPAC/Chemical Name
5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine
InChi Key
DFTCYTDJDXZFSK-JQWIXIFHSA-N
InChi Code
InChI=1S/C13H21N3O/c1-3-6-16-8-12(17-9-10(16)2)11-4-5-13(14)15-7-11/h4-5,7,10,12H,3,6,8-9H2,1-2H3,(H2,14,15)/t10-,12-/m0/s1
SMILES Code
NC1=NC=C([C@@H]2CN(CCC)[C@@H](C)CO2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 235.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Attkins N, Betts A, Hepworth D, Heatherington AC. Pharmacokinetics and elucidation of the rates and routes of N-glucuronidation of PF-592379, an oral dopamine 3 agonist in rat, dog, and human. Xenobiotica. 2010 Nov;40(11):730-42. doi: 10.3109/00498254.2010.514961. PubMed PMID: 20836725.