MedKoo Cat#: 407448 | Name: MDK83190
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDK83190, also known as Apoptosis Activator 2, is an Apoptosis Activator. MDK83190 has CAS#79183-19-0, in which the last 5 digit was used for its name for easier communication. MDK83190 has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 μM) .

Chemical Structure

MDK83190
MDK83190
CAS#79183-19-0

Theoretical Analysis

MedKoo Cat#: 407448

Name: MDK83190

CAS#: 79183-19-0

Chemical Formula: C15H9Cl2NO2

Exact Mass: 305.0010

Molecular Weight: 306.14

Elemental Analysis: C, 58.85; H, 2.96; Cl, 23.16; N, 4.58; O, 10.45

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 4,250.00 2 Weeks
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Related CAS #
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Synonym
Apoptosis Activator 2; AAII; N-(3,4-dichlorobenzyl) Isatin. MDK83190; MDK-83190; MDK 83190.
IUPAC/Chemical Name
1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione
InChi Key
KGRJPLRFGLMQMV-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2
SMILES Code
O=C1N(CC2=CC=C(Cl)C(Cl)=C2)C3=C(C=CC=C3)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 306.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nguyen JT, Wells JA. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8. Epub 2003 Jun 13. PubMed PMID: 12808146; PubMed Central PMCID: PMC164621.