MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 528812 | Name: Ampreloxetine (discontinued)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

This product is discontinued for commercial reason.

Chemical Structure

Ampreloxetine (discontinued)
Ampreloxetine (discontinued)
CAS#1227056-84-9 (free)

Theoretical Analysis

MedKoo Cat#: 528812

Name: Ampreloxetine (discontinued)

CAS#: 1227056-84-9 (free)

Chemical Formula: C18H19ClF3NO

Exact Mass: 357.1107

Molecular Weight: 357.80

Elemental Analysis: C, 60.42; H, 5.35; Cl, 9.91; F, 15.93; N, 3.91; O, 4.47

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
1227056-84-9 (free base); 1227056-87-2 (HCl)
Synonym
TD-9855; TD9855; TD 9855; Ampreloxetine;
IUPAC/Chemical Name
4-(2-((2,4,6-trifluorophenoxy)methyl)phenyl)piperidine hydrochloride
InChi Key
RVUPIJWDTBFULZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H18F3NO.ClH/c19-14-9-16(20)18(17(21)10-14)23-11-13-3-1-2-4-15(13)12-5-7-22-8-6-12;/h1-4,9-10,12,22H,5-8,11H2;1H
SMILES Code
FC1=C(OCC2=CC=CC=C2C3CCNCC3)C(F)=CC(F)=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 357.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Smith JA, Bourdet DL, Daniels OT, Ding YS, Gallezot JD, Henry S, Kim KH, Kshirsagar S, Martin WJ, Obedencio GP, Stangeland E, Tsuruda PR, Williams W, Carson RE, Patil ST. Preclinical to clinical translation of CNS transporter occupancy of TD-9855, a novel norepinephrine and serotonin reuptake inhibitor. Int J Neuropsychopharmacol. 2014 Dec 13;18(2). pii: pyu027. doi: 10.1093/ijnp/pyu027. Erratum in: Int J Neuropsychopharmacol. 2015 Apr;18(6). pii: pyv033. doi: 10.1093/ijnp/pyv033. Patil, D L [corrected to Bourdet, D L]. PubMed PMID: 25522383; PubMed Central PMCID: PMC4368888.