LY339434 | CAS#219566-62-8 | GluR5 Receptor Agonist

MedKoo Cat#: 532162 | Name: LY339434

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY339434 is a potent and selective agonist of the kainate receptor GluK1, GluR5.

Chemical Structure

LY339434

CAS#219566-62-8

Theoretical Analysis

MedKoo Cat#: 532162

Name: LY339434

CAS#: 219566-62-8

Chemical Formula: C18H19NO4

Exact Mass: 313.1314

Molecular Weight: 313.35

Elemental Analysis: C, 69.00; H, 6.11; N, 4.47; O, 20.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LY339434; LY 339434 ; LY-339434.

IUPAC/Chemical Name

2-amino-4-[(2E)-3-(naphthalen-2-yl)prop-2-en-1-yl]pentanedioic acid

InChi Key

KNAYYBRIBNEIAL-ONEGZZNKSA-N

InChi Code

InChI=1S/C18H19NO4/c19-16(18(22)23)11-15(17(20)21)7-3-4-12-8-9-13-5-1-2-6-14(13)10-12/h1-6,8-10,15-16H,7,11,19H2,(H,20,21)(H,22,23)/b4-3+

SMILES Code

O=C(O)C(N)CC(C/C=C/C1=CC=C2C=CC=CC2=C1)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 313.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Moldrich RX, Cheung NS, Pascoe CJ, Baker SR, Pedregal C, Beart PM. Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons. Brain Res. 2000 Apr 17;862(1-2):270-5. PubMed PMID: 10799698. 2: Small B, Thomas J, Kemp M, Hoo K, Ballyk B, Deverill M, Ogden AM, Rubio A, Pedregal C, Bleakman D. LY339434, a GluR5 kainate receptor agonist. Neuropharmacology. 1998 Oct-Nov;37(10-11):1261-7. PubMed PMID: 9849663.