MedKoo Cat#: 407417 | Name: eCF-309
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

eCF-309 is a potent mTOR inhibitor (IC50 = 15 nM).

Chemical Structure

eCF-309
eCF-309
CAS#2001571-40-8

Theoretical Analysis

MedKoo Cat#: 407417

Name: eCF-309

CAS#: 2001571-40-8

Chemical Formula: C18H21N7O3

Exact Mass: 383.1706

Molecular Weight: 383.41

Elemental Analysis: C, 56.39; H, 5.52; N, 25.57; O, 12.52

Price and Availability

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2mg USD 350.00 2 Weeks
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Related CAS #
No Data
Synonym
eCF-309; eCF 309; eCF309; ECF-309; ECF 309; ECF309.
IUPAC/Chemical Name
3-(2-Amino-5-benzoxazolyl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChi Key
PSICWGWNIOOULV-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H21N7O3/c1-3-26-13(27-4-2)8-25-17-14(16(19)21-9-22-17)15(24-25)10-5-6-12-11(7-10)23-18(20)28-12/h5-7,9,13H,3-4,8H2,1-2H3,(H2,20,23)(H2,19,21,22)
SMILES Code
NC1=C2C(N(CC(OCC)OCC)N=C2C3=CC=C(OC(N)=N4)C4=C3)=NC=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 383.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Fraser et al (2016) eCF309: a potent, selective and cell-permeable mTOR inhibitor Med.Chem.Commun. 4 471.