PPD 10558 | RBx 10558 | CAS#805241-79-6 | HMG-CoA reductase inhibitor

MedKoo Cat#: 529010 | Name: PPD 10558

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PPD 10558, also known as RBx 10558, is a HMG-CoA reductase inhibitor potentially for treatment of primary hypercholesterolemia.

Chemical Structure

PPD 10558

CAS#805241-79-6

Theoretical Analysis

MedKoo Cat#: 529010

Name: PPD 10558

CAS#: 805241-79-6

Chemical Formula: C34H37FN2O6

Exact Mass: 588.2636

Molecular Weight: 588.68

Elemental Analysis: C, 69.37; H, 6.34; F, 3.23; N, 4.76; O, 16.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PPD-10558; RBx-10558; PPD10558; RBx10558; PPD 10558; RBx 10558, bemfivastatin

IUPAC/Chemical Name

7-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid

InChi Key

PMFRPLBQEYHUMG-UHFFFAOYSA-N

InChi Code

InChI=1S/C34H37FN2O6/c1-21(2)32-31(34(43)36-26-14-8-22(20-38)9-15-26)30(23-6-4-3-5-7-23)33(24-10-12-25(35)13-11-24)37(32)17-16-27(39)18-28(40)19-29(41)42/h3-15,21,27-28,38-40H,16-20H2,1-2H3,(H,36,43)(H,41,42)

SMILES Code

O=C(O)CC(O)CC(O)CCN1C(C2=CC=C(F)C=C2)=C(C3=CC=CC=C3)C(C(NC4=CC=C(CO)C=C4)=O)=C1C(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 588.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Faqi AS, Prohaska D, Lopez R, McIntyre G. Developmental toxicity of the HMG-CoA reductase inhibitor (PPD10558) in rats and rabbits. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb;95(1):23-37. doi: 10.1002/bdrb.20337. PubMed PMID: 22006546.