ARH-049020 | X-334 | CAS#251454-45-2 | Peroxisome Proliferator-Activated Receptor (PPAR) Agonist

MedKoo Cat#: 528318 | Name: ARH-049020

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARH-049020, also known as X-334, is a peroxisome proliferator-activated receptor (PPAR) agonist potentially for the treatment of insulin resistance and type 2 diabetes.

Chemical Structure

ARH-049020

CAS#251454-45-2

Theoretical Analysis

MedKoo Cat#: 528318

Name: ARH-049020

CAS#: 251454-45-2

Chemical Formula: C24H31NO6

Exact Mass: 429.2151

Molecular Weight: 429.51

Elemental Analysis: C, 67.11; H, 7.28; N, 3.26; O, 22.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ARH-049020; ARH049020; ARH 049020; X-334; X 334; X334

IUPAC/Chemical Name

(S)-3-(4-(4-((tert-butoxycarbonyl)amino)phenethoxy)phenyl)-2-ethoxypropanoic acid

InChi Key

QNDFBOXBUCDYNZ-NRFANRHFSA-N

InChi Code

InChI=1S/C24H31NO6/c1-5-29-21(22(26)27)16-18-8-12-20(13-9-18)30-15-14-17-6-10-19(11-7-17)25-23(28)31-24(2,3)4/h6-13,21H,5,14-16H2,1-4H3,(H,25,28)(H,26,27)/t21-/m0/s1

SMILES Code

O=C(O)[C@@H](OCC)CC1=CC=C(OCCC2=CC=C(NC(OC(C)(C)C)=O)C=C2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 429.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Edgley AJ, Thalén PG, Dahllöf B, Lanne B, Ljung B, Oakes ND. PPARgamma agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats. Eur J Pharmacol. 2006 May 24;538(1-3):195-206. PubMed PMID: 16674938.