Hydronidone | F-351 | CAS#851518-71-3 | Non-Steroidal Antiinflammatory Drugs (NSAIDs)

MedKoo Cat#: 529104 | Name: Hydronidone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydronidone, also known as F-351, are Non-Steroidal Antiinflammatory Drugs (NSAIDs) potentially for the treatment of hepatic fibrosis.

Chemical Structure

Hydronidone

CAS#851518-71-3

Theoretical Analysis

MedKoo Cat#: 529104

Name: Hydronidone

CAS#: 851518-71-3

Chemical Formula: C12H11NO2

Exact Mass: 201.0790

Molecular Weight: 201.22

Elemental Analysis: C, 71.63; H, 5.51; N, 6.96; O, 15.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

F-351; F351; F 351

IUPAC/Chemical Name

1-(4-hydroxyphenyl)-5-methylpyridin-2(1H)-one

InChi Key

NETTXQJYJRFTFS-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H11NO2/c1-9-2-7-12(15)13(8-9)10-3-5-11(14)6-4-10/h2-8,14H,1H3

SMILES Code

O=C1C=CC(C)=CN1C2=CC=C(O)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 201.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Liu Y, Wu J, Li Z, Luo Y, Zeng F, Shi S. Tolerability and Pharmacokinetics of Hydronidone, an Antifibrotic Agent for Hepatic Fibrosis, after Single and Multiple Doses in Healthy Subjects: an Open-Label, Randomized, Dose-Escalating, First-in-Human Study. Eur J Drug Metab Pharmacokinet. 2017 Feb;42(1):37-48. doi: 10.1007/s13318-015-0316-z. PubMed PMID: 26797810.