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MedKoo Cat#: 529214 | Name: GM-608

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GM-604, also known as alirinetide, is potentially for the treatment of amyotrophic lateral sclerosis, and ischemic stroke.

Chemical Structure

GM-608
GM-608
CAS#725715-18-4

Theoretical Analysis

MedKoo Cat#: 529214

Name: GM-608

CAS#: 725715-18-4

Chemical Formula: C36H54N12O9

Exact Mass: 798.4100

Molecular Weight: 798.90

Elemental Analysis: C, 54.12; H, 6.81; N, 21.04; O, 18.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GM-604; GM-602; GM-603; GM-605; GM-606; GM-607; GM-608; GM-609; GM-6; GM604; GM602; GM603; GM605; GM606; GM607; GM608; GM609; GM6; GM 604; GM 602; GM 603; GM 605; GM 606; GM 607; GM 608; GM 609; GM 6; alirinetide
IUPAC/Chemical Name
L-phenylalanyl-L-seryl-L-arginyl-L-tyrosyl-L-alanyl-L-arginine
InChi Key
WVPOPWDCSFQEBI-HJJAOGADSA-N
InChi Code
InChI=1S/C36H54N12O9/c1-20(29(51)46-26(34(56)57)10-6-16-43-36(40)41)44-32(54)27(18-22-11-13-23(50)14-12-22)47-31(53)25(9-5-15-42-35(38)39)45-33(55)28(19-49)48-30(52)24(37)17-21-7-3-2-4-8-21/h2-4,7-8,11-14,20,24-28,49-50H,5-6,9-10,15-19,37H2,1H3,(H,44,54)(H,45,55)(H,46,51)(H,47,53)(H,48,52)(H,56,57)(H4,38,39,42)(H4,40,41,43)/t20-,24-,25-,26-,27-,28-/m0/s1
SMILES Code
N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 798.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tomlin JL, Guinn BA, Penn LZ, Berinstein NL. Bcl-2 and c-Myc co-operate in the Epstein-Barr virus-immortalized human B-cell line GM607 but do not confer tumorigenicity. Leuk Lymphoma. 2005 Apr;46(4):581-92. PubMed PMID: 16019487. 2: Giometti CS, Willard KE, Anderson NL. Cytoskeletal proteins from human skin fibroblasts, peripheral blood leukocytes, and a lymphoblastoid cell line compared by two-dimensional gel electrophoresis. Clin Chem. 1982 Apr;28(4 Pt 2):955-61. PubMed PMID: 7200412. 3: Lautner-Rieske A, Huber C, Meindl A, Pargent W, Schäble KF, Thiebe R, Zocher I, Zachau HG. The human immunoglobulin kappa locus. Characterization of the duplicated A regions. Eur J Immunol. 1992 Apr;22(4):1023-9. PubMed PMID: 1551402. 4: Giometti CS, Anderson NL. Tropomyosin heterogeneity in human cells. J Biol Chem. 1984 Nov 25;259(22):14113-20. PubMed PMID: 6501290. 5: Gemmell MA, Anderson NL. Lymphocyte, monocyte, and granulocyte proteins compared by use of two-dimensional electrophoresis. Clin Chem. 1982 Apr;28(4 Pt 2):1062-6. PubMed PMID: 6951654. 6: Dolby TW, Devuono J, Croce CM. Cloning and partial nucleotide sequence of human immunoglobulin mu chain cDNA from B cells and mouse-human hybridomas. Proc Natl Acad Sci U S A. 1980 Oct;77(10):6027-31. PubMed PMID: 6777778; PubMed Central PMCID: PMC350206.