JNJ1930942 | CAS#929562-28-7

MedKoo Cat#: 531983 | Name: JNJ1930942

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ1930942 is a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Chemical Structure

JNJ1930942

CAS#929562-28-7

Theoretical Analysis

MedKoo Cat#: 531983

Name: JNJ1930942

CAS#: 929562-28-7

Chemical Formula: C16H11F4N3OS

Exact Mass: 369.0559

Molecular Weight: 369.34

Elemental Analysis: C, 52.03; H, 3.00; F, 20.58; N, 11.38; O, 4.33; S, 8.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

JNJ1930942; JNJ 1930942; JNJ-1930942.

IUPAC/Chemical Name

(2-{[4-fluoro-3-(trifluoromethyl)phenyl]amino}-4-(pyridin-4-yl)-1,3-thiazol-5-yl)methanol

InChi Key

JBSVHWCIKVSTTH-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H11F4N3OS/c17-12-2-1-10(7-11(12)16(18,19)20)22-15-23-14(13(8-24)25-15)9-3-5-21-6-4-9/h1-7,24H,8H2,(H,22,23)

SMILES Code

OCC1=C(C2=CC=NC=C2)N=C(NC3=CC=C(F)C(C(F)(F)F)=C3)S1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 369.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dinklo T, Shaban H, Thuring JW, Lavreysen H, Stevens KE, Zheng L, Mackie C, Grantham C, Vandenberk I, Meulders G, Peeters L, Verachtert H, De Prins E, Lesage AS. Characterization of 2-[[4-fluoro-3-(trifluoromethyl)phenyl]amino]-4-(4-pyridinyl)-5-thiazolemethanol (JNJ-1930942), a novel positive allosteric modulator of the {alpha}7 nicotinic acetylcholine receptor. J Pharmacol Exp Ther. 2011 Feb;336(2):560-74. doi: 10.1124/jpet.110.173245. PubMed PMID: 21084390.