IBC 293 | CAS#306935-41-1 |GPR109B Agonist

MedKoo Cat#: 531961 | Name: IBC 293

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IBC 293 is a highly selective agonist for GPR109B (HM74), human orphan G-protein-coupled receptor expressed in adipocytes. IBC 293 is selective for GPR109B over niacin receptor GPR109A (HM74A).

Chemical Structure

IBC 293

CAS#306935-41-1

Theoretical Analysis

MedKoo Cat#: 531961

Name: IBC 293

CAS#: 306935-41-1

Chemical Formula: C10H11N3O2

Exact Mass: 205.0851

Molecular Weight: 205.22

Elemental Analysis: C, 58.53; H, 5.40; N, 20.48; O, 15.59

Price and Availability

Size	Price	Availability
1g	USD 250.00	2 Weeks
5g	USD 650.00	2 Weeks
10g	USD 950.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

IBC 293; IBC293; IBC-293.

IUPAC/Chemical Name

1-propan-2-ylbenzotriazole-5-carboxylic acid

InChi Key

RUTVRAJKELSHCC-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H11N3O2/c1-6(2)13-9-4-3-7(10(14)15)5-8(9)11-12-13/h3-6H,1-2H3,(H,14,15)

SMILES Code

O=C(C1=CC=C(N(C(C)C)N=N2)C2=C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

A selective agonist of GPR109B.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMF	16.0	77.97
	DMF:PBS (pH 7.2) (1:1)	0.5	2.44
	DMSO	25.0	121.82
	Ethanol	5.0	24.36

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 205.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Mazzola E, Cheng SC, Parmigiani G. The penetrance of ductal carcinoma in situ among BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2013 Jan;137(1):315-8. doi: 10.1007/s10549-012-2345-5. PubMed PMID: 23184082; PubMed Central PMCID: PMC3836600.