MedKoo Cat#: 531949 | Name: HJC 0350
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HJC 0350 is a selective Epac2 inhibitor (IC50 = 0.3 μM). HJC 0350 displays no effect on Epac1. HJC 0350 blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.

Chemical Structure

HJC 0350
HJC 0350
CAS#885434-70-8

Theoretical Analysis

MedKoo Cat#: 531949

Name: HJC 0350

CAS#: 885434-70-8

Chemical Formula: C15H19NO2S

Exact Mass: 277.1136

Molecular Weight: 277.38

Elemental Analysis: C, 64.95; H, 6.90; N, 5.05; O, 11.54; S, 11.56

Price and Availability

Size Price Availability Quantity
5mg USD 250.00 2 Weeks
10mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
HJC 0350; HJC0350; HJC-0350.
IUPAC/Chemical Name
2,4-dimethyl-1-(2,4,6-trimethylphenyl)sulfonylpyrrole
InChi Key
AFZWZVLPIMHLSE-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H19NO2S/c1-10-6-12(3)15(13(4)7-10)19(17,18)16-9-11(2)8-14(16)5/h6-9H,1-5H3
SMILES Code
O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 277.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Chen et al (2013) Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 56 952. PMID: 23286832.