Synonym
Tyroservatide; YSV; CMS-024-02; CMS 024 02; CMS02402
IUPAC/Chemical Name
(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxy-propanoyl]amino]-3-methyl-butanoic acid
InChi Key
TYFLVOUZHQUBGM-IHRRRGAJSA-N
InChi Code
InChI=1S/C17H25N3O6/c1-9(2)14(17(25)26)20-16(24)13(8-21)19-15(23)12(18)7-10-3-5-11(22)6-4-10/h3-6,9,12-14,21-22H,7-8,18H2,1-2H3,(H,19,23)(H,20,24)(H,25,26)/t12-,13-,14-/m0/s1
SMILES Code
CC(C)[C@H](NC([C@@H](NC([C@@H](N)CC1=CC=C(O)C=C1)=O)CO)=O)C(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
367.40
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Che XC, Lu R, Hu JX, Zheng MN, Zhang MF, Wang S, Yu CY, Yang XL, Xing DH, Yao
Z. [Inhibitory effect of tripeptide compound tyroservaltide on invasion and
metastasis of mouse melanoma cell line B16-F10]. Ai Zheng. 2006 Mar;25(3):275-80.
Chinese. PubMed PMID: 16536978.
2: Jia J, Lu R, Qiu S, Li H, Che X, Zhao P, Jin M, Yang H, Lin G, Yao Z.
Preliminary investigation of the inhibitory effects of the tyroservaltide (YSV)
tripeptide on human hepatocarcinoma BEL-7402. Cancer Biol Ther. 2005
Sep;4(9):993-7. PubMed PMID: 16082190.
